San Francisco 49ers 2021 schedule: Predicting every game, opponent win totals, record projection | CBS Sports Headlines San Francisco 49ers 2021 schedule: Predicting every game, opponent win totals, record projection How will San Francisco fare this year? Assessing all 17 games for the 49ers ESN FeedsThis post was originally published … Continue reading San Francisco 49ers 2021 schedule: Predicting every game, opponent win totals, record projection