Kyle Shanahan says 49ers rookie Brandon Aiyuk has a high ankle sprain, will miss rest of season | CBS Sports Headlines Kyle Shanahan says 49ers rookie Brandon Aiyuk has a high ankle sprain, will miss rest of season Aiyuk had a strong rookie season as injuries ravaged the San Francisco … Continue reading Kyle Shanahan says 49ers rookie Brandon Aiyuk has a high ankle sprain, will miss rest of season