Giants vs. 49ers odds, line, spread: Thursday Night Football picks, NFL predictions by model on 164-117 run | CBS Sports Headlines Giants vs. 49ers odds, line, spread: Thursday Night Football picks, NFL predictions by model on 164-117 run SportsLine’s model simulated San Francisco vs. New York 10,000 times with Saquon … Continue reading Giants vs. 49ers odds, line, spread: Thursday Night Football picks, NFL predictions by model on 164-117 run